Thursday, October 22, 2015

There are many studies on Origin of cultivated plants, one of earliest being Origin of Cultivated Plants by Alphonse de Candolle, a Swiss botanist. Later N.I Viplov recognized eight centers of diversity of cultivated plants, with some originating in more than one center. Jack R Harlan later studied and concluded that some crops do not have center of origin and associated crop origin with regions. Six major regions of crop origin identified are as below.
  1. 1.      Near-Eastern Region: Barley, wheat, garden pea, lentil, chickpea etc.
  2. 2.      Chinese Region: Bamboo, Peach, Litchi, walnut, persimmon, ginger, gourds etc.
  3. 3.      African Continent: Yam, Sorghum, okra, coffee, cotton etc.
  4. 4.      South Asia and island: Eggplant, Mango, Banana, citrus, cardamom etc.
  5. 5.      North America: Sunflower, Cranberry, Blueberry and Tobacco etc.
  6. 6.      South and Central America:  Corn, peanut, white potato, cashew, pineapple, papaya etc.

 Food and Agriculture Organization (FAO) of United Nations estimates 40 countries have large amount of food insufficient for their population. This account almost 1 out of 7 billion of total population of world. In one part of the world excessive food and obesity is becoming a serious problem day by day, in other part (developing and least developed countries) people are dying out of hunger. In contrary to this, human population is growing and mouths to feed has increased, at the same time, land to grow is becoming limited. It comes with a challenging situation to plant science to develop high yielding and disease/pest resistant crops.
A series of improvement in plant sciences has been found. Since the beginning of civilization and domestication of agricultural practices, selection of crops for better traits and high productivity continued. This was noticed clearly after Mendel’s work in nineteenth century. By then, selection was the established method for improvement in crop breeding. A good example here comes from Corn (Zea mays), which is a modern crop introduced from years long selection process of Teosinte (Zea Mexicana). Now corn is totally dependent on humans for survival. Selection is still a prominent and effective method of crop improvement in plant breeding.
Early part of twenty century in United States was a productive era in plant breeding science. This led to development of high yielding varieties, which need higher doses of fertilizers, pesticides, mechanization and irrigation. Transformation for these technologies continued to developing countries over past 40 years, which led to higher productivity in agriculture production system. This achievement is known as Green Revolution.
Dr. Norman Borlaug led green revolution was possible due to development of high-yield varieties. Development and extension of dwarf strain of wheat in Mexico (by CYMMIT) and rice in Philippines (IRRI).  At the same time disease-resistant varieties of crops which are able to stand against many bacteria, fungi, viruses and nematodes were developed.  It was a breakthrough in agricultural science, the benefit of this spread away to Asia and Africa too. Countries like India, Pakistan and china were benefited largely by this.
Green revolution was not a miracle without high rate of input supply. Thus, there came some problems, mostly in developing countries. Critics blame green revolution as a costlier technique and environmentally not safe. More on this, genetic diversity of the plants are also eroded. As there needed high dose of pesticides and fertilizer, adequate irrigation and high mechanization, developing part of the world suffered from inadequacy. This lead to salinity in soil.
Solution to problem led by green revolution should start from the part of the world where population is very high. Development in improved irrigation system, organic fertilizers, biological control of pest and diseases may reduce the negative impact of green revolution by a large part.
Erosion of genetic diversity starts from monoculture practices. Monoculture is growing the same crop year after year in a large region. Not only crop, this has narrowed down to some selected varieties of crops only. For example, half of the wheat acreage in the United States is planted with just nine varieties of wheat.  Sustainable agriculture on other hand consist of mixture of annual and perennial crops, which can be harvested for a number of years without replanting.
As traditional varieties ( land races) are abandoned and replaced with modern , high yielding varieties and as habitat destruction brings about the extinction of wild relatives, valuable genetic heritage is lost forever, which is known as genetic erosion. This erosion can be reduced by gene or seed banks. In U.S. seed bank is located at National Centre for Genetic Resources Preservation in Fort Collins, Colorado under USDA in 1958. More than 500,000 seed samples representing 8,000 species are housed there.  Liquid nitrogen under at very low temperature is used as preservative. Heirloom varieties or traditional varieties are encouraged to cultivate for their preservation.
Germplasm is the encoded information of a plant, the genetic instructions that dictate not only the type of the plant but also all the traits unique to an individual plant. Germplasm is the center of an international controversy, the question of ownership.   In June 2004, the international Treaty of Plant Genetic Resources for Food and Agriculture was enacted to protect valuable genetic resources. Ratified by 55 nations, the treaty defines plant genetic resources as “any genetic material of plant origin of actual or potential value for food and agriculture.”
FAO has identified some of the potential alternative crops. Alternative crops can be brought to the attention of global agriculture and can be diversify the world’s food sources. Quinoa is one of them, which is found in South America.  Grain amaranth is another new world crop under development for world market.   A South America legume called Tarwi has been taken in interest in recent days.  Similarly Tamarillo and naranjilla two relatives of tomatoes are also identified as good alternative to vegetables supply. Tamarillo is tree tomato. Oca is a tuber crop as of wheat potato, which is from Andes.
Biotechnology is use of living organism to provide products for humanity. Cell and tissue culture is one of the established biotechnology technique where whole plant is developed from a single cells. Small pieces of plant tissues are grown in a nutrient medium supplemented with plant hormones, after a few days, the cells begin dividing and produce a small, undifferentiated mass of tissue known as a callus.  Similarly molecular plant breeding technique uses marker assisted selection process for identification and incorporation of some special traits that are not identifiable through phenotype.
The genetic engineering, especially the recombinant DNA technology is a new and major changing technology in field of plant breeding.   While traditional methods of plant breeding allows the transfer of useful genes within a species or closely related species, genetic engineering  allows the transfer of useful genes from one organism to a totally unrelated plant species. Organism with foreign gene are called transgenic.  The development of transgenic plants begins with the identification and isolation of the useful trait containing gene and useful vector to transfer that. Use of Plasmids or gene gun shoot can be done for gene transfer.
Genetic engineering has two major traits developed in plants. First one is herbicide resistance.   Bacterial gene that confers resistance to the herbicide glyphosate has been introduced in many plants.  However there are lot of cases where farmers are against the developer of these kind of traits. In 2002, Monsanto a seed company which developed herbicide resistant wheat variety was objected by farmers. Country like Japan and South Korea objected those wheat crops containing herbicide resistant. Insect resistance is another trait that is developed in crops through genetic engineering. Bacillus thuringiensis (Bt) a common soil bacterium is used for insect resistance trait.
There is widespread adoption of Bt corn, as it is resistant to European corn borer. A study in 1990 at Cornell University charged the Bt corn for harming monarch butterfly population. There are subsequent studies, which proves that fining was not correct. However, this controversy is still there. The genetic engineered golden rice which contains Beta Carotene (converts into Vitamin A) is being developed as a new tool to eradicate malnutrition problem.  Later Bill and Melinda Gates Foundation has funded for addition of vitamin E, more protein and enhanced iron and zinc availability in same rice variety.
There are many crops beyond staple food which are genetically engineered like soybean, alfalfa, tomato, and canola. New traits like disease resistance is being developed in genetically engineered crops.  Genetic engineering being used to produce rice plants resistant to a devastating disease called leaf blight, caused by the bacterium Xanthomonas oryzae.
The scope of biotechnology extends beyond food crops. One of the promising use is in pharmaceuticals to produce many vaccines and medicines. Also, since 1990s, there are a lot of ongoing greenhouse and field trials of GM trees in 16 countries. In 2010 USDA approved for eucalyptus tree.
There are many issues with GM crops. Issue on regulation is one of them. In 1992 Food and Drug Administration (FDA) developed a policy on GE crops, recommending that “developers consults with FDA about bio-engineering foods under development”.  If the FDA feels that GM variety is not safe for marketing comparing with other non GM food, by testing 120 days before that food is marketed, there would be ban on marketing. Environmental Protection Agency (EPA) evaluates any possible effects on non-target organism. The U.S. Department of Agriculture (USDA) monitors the field crops that are genetically engineered.
Critics argue that GM crops are seriously affecting our environment, can harm human health and benefits only large agribusiness conglomerates. GM crops are questioned all over the world. Zambia refused US food aid in 2002 with fear of GM. European countries were more cautious, however, recent days they started to grow GM crops. There is concerns over transfer of herbicide resistant gees from GM crops to other related species. Also, natural development resistant in weeds are also questioned.  Use of terminator gene is also questioned seriously in developing nations, so that same seed cannot be planted and has to depend on seed companies year after year. So there is also blame for super insect development and killer weeds development having developed the resistance against GM. Though there are any issues against GM, the National Research Council in 2010 resealed a report saying on impact of GM crops in American farmers. The report has found economic and environmental benefits rather than harm.
In conclusion, there are questions against use of Biotechnology. However, biotechnology is found useful in many ways. It is  needed to feed the growing population which signifies there would be further development in biotechnology in days to come.



A college dropout but visionary inventor Steve p. Jobs (1955-2011) has given a lot to information technology sector globally. His seek to invent “insanely great” products has really made “dent on universe” as envisioned. Products like Mac computer, iPod, iPhone and iPad are today among millions of people worldwide. These revolutionary products are result of serious effort of Steve P. Jobs.

Steve was born in San Francisco, California from Joanne Scheible and adapted by Clara and Paul Jobs with promise to send him to college. Steve was inquisitive, energetic and imaginative. His first learning was more in his father’s garage than schools he attended. Steve meet a true friend sharing the same type of interest on electronics; Steve Wozniak. During high school period he was almost living a hippie style of life. He had no money even for food. He dropped for college study and joined calligraphy where he inspired toward Zen Buddhism by Robert Friedland. He went to India for seeking enlightenment through meditation. He wanted to meet guru Neem Karoli Baba. Once he could not find Neem Karoli Baba , he realized something different. He thought " maybe Thomas Edison did a lot more to improve the world than Karl Marx and Neem Karoli Baba put together". Then he decided to find his own guru.

In 1975 when he was 20 years, he started to work at Atari. He and Woz both had good exposure to computers and people working on those filed around california ( now popularly known as Silicon Valley).  He convinced Woz who was working in Hewlett-Packard (HP) Company as an engineer to establish their own company. They named it “Apple”. They needed funding, for which they added Ron Wayne as 10 % of shareholder who provided almost all the money needed to run a company. For this, they made a 45-45-10 % share agreement in April 1976.

They started work at Steve’s house (father’s garage), when they got order of 50 computer, that they made from scratch. The idea of complete computer with monitor, keyboard and mouse came to their mind after annual computer festival in New Jersey. While there were shortage of money for Apple II computer Mike Markkula was ready to fund with condition that Woz leave HP Job. Then Woz left HP and Markkula was their partner. Apple II was launched with a special program and the market started to grow continuously. By the age of 25, Steve had superstar status becoming a multimillionaire. New generation computer like Macintosh and Lisa (name from Job’s daughter) was ready for market in 1984. It was launched wonderfully linking it with a novel 1984. It left a Mac-Mania effect on public. With the start of 1985, market of Apple gone down. Steve started to be harsh to worker for hard work. However, this was not entertained by John Scully and others. So they be-seized Steve's managerial role. Steve resigned in September 17, 1985.

Steve was disappointed, aloof, not talking to anyone. But slowly, he started his new business with NeXT computer and Pixar Company. He sold all the Apple shares except 1 share, for money he needed for operating new company. After Steve left the Apple, their business also gone down. After 12 years of separation from Apple, a company that Steve jobs established and nurtured, he came back to Apple in June 1997 replacing Amelia with a special request from Apple management.

This time was golden era for Apple. To make competitive and emerging he invented iPod, iPhone, iPad. Later his Pixar Company also became popular on film industry. As a CEO he had just $1 as his salary. With invention of iPod , music industry became problematic and they went to court against Steve Jobs.  That’s why Apple establish iTunes and problem was solved. 

Jobs found to have cancer in Pancreases in 2004. He operated it in 2005, but could not cure. He died on October 5, 2011 at the age of fifty six. Whichever role he played, there is no question that Steve fulfilled his dream to put a dent in the universe.

Book Details:
Title of the Book: Steve Jobs: thinking differently
Category:  A biography
Author: Patricia Lakin
175 pp, $ 15.99 US / $ 18.99 CAN
aladdin

SIMON & SCHUSTER, NEW YORK

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Badri Khanal is An Agriculture Economist from Nepal
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